If you think you may have had sex with somebody who is HIV positive without using a condom, we may offer you "PEPSE" - Post Exposure Prophylaxis following Sexual Exposure. This is a 28 day course of medication which if taken in the right circumstances can reduce your risk of HIV infection. PEPSE is most effective if taken in the first 24 hours following a possible exposure to the HIV virus but can be taken up to 72 hours afterwards. We will ask you a few questions to help us evaluate your risk and we will discuss the advantages and disadvantages of initiating this treatment depending on your individual circumstances.